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What Is Big Pharma?

Big Pharma is a term for the world’s largest publicly traded pharmaceutical companies.

The 50 largest pharmaceutical companies in the world

The world’s 50 largest pharmaceutical companies still saw a whopping $851 billion in sales in 2020, according to an analysis of financials by Drug Discovery & Development.

RankCompanyHeadquarters2020 Revenues ($USD)
1Sinopharm (pharmaceutical distribution segment)China$50,446,739,666
2Roche Pharmaceuticals (division of Roche Group)Switzerland$49,516,455,427
3NovartisSwitzerland$48,659,000,000
4MerckUSA$47,994,000,000
5AbbVieUSA$45,804,000,000
6Janssen (Johnson & Johnson’s pharmaceutical segment)USA$45,572,000,000
7GlaxoSmithKline (GSK)U.K. $43,537,603,200
8Bristol Myers SquibbUSA$42,518,000,000
9PfizerUSA$41,908,000,000
10SanofiFrance$41,086,740,000
11Takeda PharmaceuticalJapan$29,948,845,895
12AstraZenecaU.K. $26,617,000,000
13Gilead SciencesUSA$24,689,000,000
14Eli LillyUSA$24,539,800,000
15AmgenUSA$24,240,000,000
16Bayer (Pharmaceuticals Division)Germany$19,657,020,000
17Novo NordiskDenmark$19,410,703,364
18Boehringer IngelheimGermany$17,163,157,895
19Teva PharmaceuticalIsrael$16,659,000,000
20Merck KGaAGermany$16,149,714,000
21BiogenUSA$13,444,600,000
22ViatrisUSA$11,946,000,000
23Astellas PharmaJapan$11,701,891,740
24Daiichi SankyoJapan$9,014,010,114
25Otsuka Holdings (pharmaceutical business)Japan$8,945,495,411
26CSL, including CSL BehringAustralia$8,796,600,000
27Regeneron PharmaceuticalsUSA$8,497,100,000
28Bausch HealthCanada$8,027,000,000
29Chugai Pharmaceutical (Roche, majority owner)Japan$7,369,357,558
30EisaiJapan$6,514,525,192
31Vertex PharmaceuticalsUSA$6,205,683,000
32UCBBelgium$6,095,580,000
33GrifolsSpain$6,087,643,320
34Alexion PharmaceuticalsUSA$6,070,000,000
35ServierFrance$5,344,320,000
36Sumitomo Dainippon PharmaJapan$4,521,371,043
37Sun Pharmaceutical IndustriesIndia$4,514,904,235
38Abbott (Established Pharmaceutical Products)USA$4,303,000,000
39MenariniItaly$4,275,000,000
40Jiangsu Hengrui Medicine Co.China$4,017,120,014
41Sino BiopharmaceuticalChina$3,418,209,206
42ShionogiJapan$3,122,035,962
43Aurobindo PharmaIndia$3,115,402,823
44CatalentUSA$3,094,300,000
45IpsenFrance$3,062,268,000
46Endo InternationalIreland$2,903,074,000
47H. LundbeckDenmark$2,702,140,673
48IncyteUSA$2,666,702,000
49Jazz PharmaceuticalsIreland$2,363,567,000
50Dr. Reddy’s LaboratoriesIndia$2,354,911,934

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